Preparation, Characterization, and In Vivo Pharmacoscintigraphy Evaluation of an Intestinal Release Delivery System of Prussian Blue for Decorporation of Cesium and Thallium
نویسندگان
چکیده
منابع مشابه
Preparation, Characterization, and In Vivo Pharmacoscintigraphy Evaluation of an Intestinal Release Delivery System of Prussian Blue for Decorporation of Cesium and Thallium
Background Prussian blue (PB, ferric hexacyanoferrate) is approved by US-FDA for internal decorporation of Cesium-137 (137Cs) and Thallium-201 (201Tl). Aim Since PB is a costly drug, pH-dependent oral delivery system of PB was developed using calcium alginate matrix system. Methods Alginate (Alg) beads containing PB were optimized by gelation of sodium alginate with calcium ions and effect ...
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ژورنال
عنوان ژورنال: Journal of Drug Delivery
سال: 2017
ISSN: 2090-3014,2090-3022
DOI: 10.1155/2017/4875784